A novel synthesis of 2-amino- and 2-hydroxycarbazoles
✍ Scribed by Jan Bergman; René Carlsson
- Book ID
- 104246161
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 193 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
Thmlytic cyclizationof thereadilyavailableccmpounl~givesellipticine (2) in goodyieldanlanisamzr,assigned structure 2, in varlaus amunts ( &reef 1). potentially interestjngcapmd [ cfref 2where the azaanalogue$isdescribed) wirq rapid, high-yield routewas developed. w 1 C,% C,% *This -alsodeserves interestasademsaanal cgue of 3 -mim-l,4-dime~l-5H-pyrido-[4,3-b] jndole, which recently has been reported 15,16 tobehighlynuwgenic.
📜 SIMILAR VOLUMES
Diels-Alder reaction of 3-and 2-nitroindoles with Danishefsky's diene gives the expected 2-and 3-hydroxycarbazoles in very good to excellent yields (73-91%) and with apparent complete regioselectivity.