𝔖 Bobbio Scriptorium
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A novel surgical approach towards survival after gene delivery in the mouse

✍ Scribed by Warren D. Rosenblum; Won Lee; Carol Weis; Bo Sun

Book ID
119589324
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
108 KB
Volume
4
Category
Article
ISSN
1532-8414

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## Abstract Summary: The presence in an intron of the ploxP‐neo‐loxP cassette often results in severe interference with gene expression. Consequently, many investigators selectively remove the ploxP‐neo‐loxP cassette by transient expression of Cre in ES cells. Although effective, the added manipula