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A Novel Stereoselective Total Synthesis of (+)‐5‐ epi ‐Cytoxazone

✍ Scribed by Swamy, Navath Raghavendra; Krishnaiah, Pendem; Reddy, Natala Srinivasa; Venkateswarlu, Yenamandra


Book ID
120473611
Publisher
Taylor and Francis Group
Year
2004
Tongue
English
Weight
124 KB
Volume
23
Category
Article
ISSN
0732-8303

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A Highly Stereoselective Total Synthesis
✍ Chiara Zanato; Luca Pignataro; Andrea Ambrosi; Zhongyan Hao; Cesare Gennari 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 192 KB

## Abstract The total synthesis of (+)‐9‐__epi__‐dictyostatin (**1b**), a diastereomer of the antimitotic marine‐sponge‐derived macrolide (–)‐dictyostatin (**1a**), was achieved by creating 11 stereogenic centers and 4 stereogenic double bonds with a high level of stereocontrol. The yield for the 2