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A Novel Stereoselective Cyclization to Functionalized Dihydropyrans

✍ Scribed by Viswanathan, Ganapathy S.; Yang, Jun; Li, Chao-Jun


Book ID
121860819
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
97 KB
Volume
1
Category
Article
ISSN
1523-7060

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Stereoselective tandem Michael-intramole
✍ Adelfo Reyes; Ignacio Regla; Mabel C Fragoso; Laura A Vallejo; Patricia Demare; πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 787 KB

A stereoselective synthesis of pyrrolo[2,1-a]isoindoi-5-ones is described. The synthesis takes place through a tandem Michael addition-intramolecular cyclization, by the basepromoted condensation of methyl N-phthaloylalaninate with conjugate acceptors at low temperature. The desired products were ob