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A novel stereocontrolled approach to steroid side chain construction: asymmetric synthesis of potential synthon of the vitamin D series

โœ Scribed by Hideo Nemoto; Hiroshi Kurobe; Keiichiro Fukumoto; Tetsuji Kametani

Publisher
Elsevier Science
Year
1984
Tongue
French
Weight
211 KB
Volume
25
Category
Article
ISSN
0040-4039

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An efficient new method is desccibed for the construction of the 25-hydroxy-22-oxavitamin D3 side-chain, which is present in several analogues of calcitriol with antitumour activity.