A novel stereo- and regio-controlled synthesis of 2-deoxy-α-O-aryl glucosides
✍ Scribed by Giuseppe Capozzi; Chiara Falciani; Stefano Menichetti; Cristina Nativi; Richard W. Franck
- Book ID
- 103428392
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 379 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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## Abstract magnified image A new set of 2,3,4,5‐tetrasubstituted isoxazolidines with an α,β‐unsaturated carbonyl function at position 4 has been synthesized. The multicomponent approach and microwave irradiation protocol have also been investigated for the above synthesis.
The synthesis of 2-phenyl-3-aryl and 2-phenyl-3-aroyl derivatives 5-(1,2-O-isopropylidene-alpha-D-xylo-tetrofuranos-4-yl)isoxazolidi ne (3) from nitrones and 5,6-dideoxy-1,2-O-isopropylidene-alpha-D-xylo-hex-5- enofuranose (1) is described. The 1,3-dipolar cycloaddition reactions given mainly anti a