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A novel splice mutation of HERG in a Chinese family with long QT syndrome

✍ Scribed by Shang Yun-peng; Xie Xu-dong; Wang Xing-xiang; Chen Jun-zhu; Zhu Jian-hua; Tao Qian-min; Zheng Liang-rong


Publisher
SP Zhejiang University Press
Year
2005
Tongue
English
Weight
671 KB
Volume
6
Category
Article
ISSN
1673-1581

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The long QT syndrome (LQTS) is a cardiac disorder characterized by prolongation of the QT interval on electrocardiograms (ECGs), syncope and sudden death caused by a specific ventricular tachyarrhythmia known as torsade de pointes. LQTS is caused by mutations in ion channel genes including the cardi