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A novel spin-labeled amino acid derivative for use in peptide synthesis: (9-fluorenylmethyloxycarbonyl)-2,2,6,6-tetramethylpiperidine-N-oxyl-4-amino-4-carboxylic acid

โœ Scribed by Marchetto, Reinaldo; Schreier, Shirley; Nakaie, Clovis R.


Book ID
111927314
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
218 KB
Volume
115
Category
Article
ISSN
0002-7863

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## Abstract __N__โ€[1โ€(4โ€(4โ€fluorophenyl)โ€2,6โ€dioxocyclohexylidene)ethyl] (Fde) protected amino acids have been prepared and applied in solidโ€phase peptide synthesis monitored by gelโ€phase ^19^F NMR spectroscopy. The Fde protective group could be cleaved with 2% hydrazine or 5% hydroxylamine solutio