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A novel skeletal drug delivery system using self-setting bioactive glass bone cement. III: the in vitro drug release from bone cement containing indomethacin and its physicochemical properties

โœ Scribed by Makoto Otsuka; Yoshihisa Matsuda; Tadashi Kokubo; Satoru Yoshihara; Takashi Nakamura; Takao Yamamuro

Book ID
113275597
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
694 KB
Volume
31
Category
Article
ISSN
0168-3659

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Drug release from a novel self-setting b
Drug release from a novel self-setting bioactive glass bone cement containing cephalexin and its physicochemical properties
โœ Otsuka, Makoto ;Matsuda, Yoshihisa ;Kokubo, Tadashi ;Yoshihara, Satoru ;Nakamura ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 502 KB

A novel device containing cephalexin as a model drug using a self-setting bioactive cement based on CaO-Si0,-P,O, glass was investigated. The device consisted of 95 wt/wt% glass powders and 5 wt/wt% cephalexin powder hardened within 5 min after mixing with a phosphate buffer. After setting, in vitro