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A novel silencer element repressing expression of the GLP-1 receptor gene in fibroblasts and pancreatic A-cells, but not in pancreatic B- and D-cells

✍ Scribed by Firouzeh Shoghi Galehshahi; Burkhard Göke; Brigitte Lankat–Buttgereit


Book ID
117407825
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
387 KB
Volume
21
Category
Article
ISSN
0196-9781

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## ABSTRACT Elements controlling high expression of the 17‐1A antigen gene in pancreatic carcinoma cells (Capan 2) reside within the two regions: proximal (−193 to +3) and distal (−877 to −518). We demonstrate here that some factors present in nuclear extracts from nonexpressing cells bind specific