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A novel series of chemical structures active in vitro against the trypomastigote form of Trypanosoma cruzi

✍ Scribed by David J. Hammond; Bryan Cover; Winston E. Gutteridge


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
523 KB
Volume
78
Category
Article
ISSN
0035-9203

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In this article we describe a novel approach to the application of graph theory in structure-activity relationship studies. An information-theoretical topological index for the vertices of a molecular graph has been used for the qualitative evaluation of the mutagenic activity of a series of nonfuse