✦ LIBER ✦

A Novel Series of 4-Piperidinopyridine and 4-Piperidinopyrimidine Inhibitors of 2,3-Oxidosqualene Cyclase−Lanosterol Synthase

✍ Scribed by Brown, George R.; Hollinshead, David M.; Stokes, Elaine S. E.; Waterson, David; Clarke, David S.; Foubister, Alan J.; Glossop, Steven C.; McTaggart, Fergus; Mirrlees, Donald J.; Smith, Graham J.; Wood, Robin

Book ID: 126424093
Publisher: American Chemical Society
Year: 2000
Tongue: English
Weight: 112 KB
Volume: 43
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm000139k

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: Novel 4-Piperidinop

ChemInform Abstract: Novel 4-Piperidinopyridine Inhibitors of Oxidosqualene Cyclase-Lanosterol Synthase Derived by Consideration of Inhibitor pKa.

✍ George R. Brown; Alan J. Foubister; Michael C. Johnson; Nicholas J. Newcombe; Da 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB

N-|(1,5,9)-trimethyl-decyl|-4α, 10-dimet

N-|(1,5,9)-trimethyl-decyl|-4α, 10-dimethyl-8-aza-trans-decal-3β-ol a novel potent inhibitor of 2,3-oxidosqualene cycloartenol and lanosterol cyclases

✍ M. Taton; P. Benveniste; A. Rahier 📂 Article 📅 1986 🏛 Elsevier Science 🌐 English ⚖ 360 KB

ChemInform Abstract: Synthesis and Inhib

ChemInform Abstract: Synthesis and Inhibition Studies of Sulfur-Substituted Squalene Oxide Analogues as Mechanism-Based Inhibitors of 2,3-Oxidosqualene- Lanosterol Cyclase.

✍ D. STACH; Y. F. ZHENG; A. L. PEREZ; A. C. OEHLSCHLAGER; I. ABE; G. D. PRESTWICH; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views

N-(1-Oxododecyl)-4.alpha.,10-dimethyl-8-

N-(1-Oxododecyl)-4.alpha.,10-dimethyl-8-aza-trans-decal-3.beta.-ol: a potent competitive inhibitor of 2,3-oxidosqualene cyclase

✍ Wannamaker, M. Woods; Waid, Philip P.; Van Sickle, William A.; McCarthy, James R 📂 Article 📅 1992 🏛 American Chemical Society 🌐 English ⚖ 413 KB

ChemInform Abstract: (4→4)-Di(2,3-anhydr

ChemInform Abstract: (4→4)-Di(2,3-anhydropentopyranosides), a Novel Class of Potential Enzyme Inhibitors.

✍ R. J. ABDEL-JALIL; R. A. AL-QAWASMEH; W. VOELTER 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

1998 carbohydrates carbohydrates U 0500 45 -213 (4→4)-Di(2,3-anhydropentopyranosides), a Novel Class of Potential Enzyme Inhibitors. -The new class of 4,4'-diepoxydisaccharides such as (III) is obtained by reaction of epoxy hydroxy enolate pyranosides with the corresponding triflates.

2,3-Diarylpyran-4-ones: A New Series of

2,3-Diarylpyran-4-ones: A New Series of Selective Cyclooxygenase-2 Inhibitors.

✍ Yung Hyup Joo; Jin Kwan Kim; Seon-Hwa Kang; Min-Soo Noh; Jun-Yong Ha; Jin Kyu Ch 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 113 KB 👁 1 views