Stable toxin (ST) peptides are the causative agents for a severe form of watery diarrhea. These peptides bind to a membrane-associated form of guanylyl cyclase, guanylyl cyclase C. The result is an accumulation of cyclic guanosine monophosphate (cGMP) in the intestinal cell, regulating protein kinas
A novel role for cGMP-specific phosphodiesterase, PDE6, in active transport of cGMP
β Scribed by Jonathan P Day; Miles D Houslay; Shireen-A Davies
- Publisher
- BioMed Central
- Year
- 2005
- Tongue
- English
- Weight
- 186 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1471-2210
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