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A novel risperidone-loaded SAIB–PLGA mixture matrix depot with a reduced burst release: effects of solvents and PLGA on drug release behaviors in vitro/in vivo

✍ Scribed by Xia Lin; Shenshen Yang; Jingxin Gou; Mingming Zhao; Yu Zhang; Na Qi; Haibing He; Cuifang Cai; Xing Tang; Penghong Guo

Publisher
Springer
Year
2011
Tongue
English
Weight
802 KB
Volume
23
Category
Article
ISSN
0957-4530

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PLGA nanoparticles for oral delivery of
PLGA nanoparticles for oral delivery of hydrophobic drugs: Influence of organic solvent on nanoparticle formation and release behavior In Vitro and In Vivo using estradiol as a model drug
✍ D.K. Sahana; G. Mittal; V. Bhardwaj; M.N.V. Ravi Kumar 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 741 KB

The aim of present investigation was to screen different solvents for optimizing nanoparticle preparation in terms of particle size, entrapment efficiency, and finally, release behavior using a model drug estradiol. Nanoparticles were prepared following emulsion-diffusion-evaporation method using di