A Novel Ring Transformation of Pyridinium Salts as a Route to 4-Arylpyridines

✍ Scribed by Sergey P. Gromov; Nikolai A. Kurchavov

• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 76 KB
• Volume: 2002
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/1099-0690(200212)2002:24<4123::aid-ejoc4123>3.0.co;2-m

✦ Synopsis

Regiospecific phenylation of pyridine derivatives at the 4-position takes place in the reaction of 4-methylpyridinium salts 1 with other pyridinium salts 2 by intermolecular transformation of the pyridine ring in 1 and participation of the methyl group of 2. The method developed makes it possible to carry out ring transformation not only for pyridinium salts 1 but