A Novel Ring-Opening Reaction of (Z)-2-Methyl-4-arylmethylene-5(4H)-oxazolone Derivatives with Acylhydrazines.
✍ Scribed by Kei Maekawa; Yoshitaka Kanno; Kanji Kubo; Tetsutaro Igarashi; Tadamitsu Sakurai
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 20 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
For Abstract see ChemInform Abstract in Full Text.
📜 SIMILAR VOLUMES
## Abstract The 5(4__H__)‐oxazolones 1a–e react with 5‐morpholinoisoxazoles 2a–b to afford the 4‐[(4‐isoxazolyl)methyl]‐5(4__H__)‐oxazolones 3a–g. Compounds 3 are hydrogenated with Pd/C in dioxane to yield the corresponding 1,4,5,6‐tetrahydro‐6‐oxo‐3‐pyridinecarbaldehydes 6a–d.
## Abstract An influence of a structure of the amine (benzylamine, __N__‐methyl‐benzylamine, __N__‐isopropyl‐benzylamine, __N__‐methyl‐butylamine, __N__‐ethyl‐butylamine, __sec__‐butylamine, and __tert__‐butylamine) on a rate constant of the ring‐opening reaction of 4‐benzylidene‐2‐methyl‐5‐oxazolo