A novel reaction of isocyanates with transition metal ethynyl complexes

✍ Scribed by P. Hong; K. Sonogashira; N. Hagihara

• Publisher: Elsevier Science
• Year: 1970
• Tongue: French
• Weight: 165 KB
• Volume: 11
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)98041-4

✦ Synopsis

Reactions

of nucleophilic olefins, such as enamines, ketenacetals, ketenaminals, etc., with isocyanates have received considerable attention recently(l). The olefins containing a P-hydrogen add to isocyanates to form unsaturated amides as linear adducts. Without the P-hydrogen in the olefins, 1,2-cycloaddition occurs to afford /3-lactams.