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A novel radioimmunoassay of 16α-hydroxy-dehydroepiandrosterone and its physiological levels

✍ Scribed by Ludmila Zamrazilová; Hana Kazihnitková; Oldřich Lapčík; Martin Hill; Richard Hampl


Book ID
116698026
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
271 KB
Volume
104
Category
Article
ISSN
0960-0760

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Diastereomerically pure 2-formyl-N-Boc-l,3-oxazolidine 7 was prepared in 83% yield from stannyloxazolidine 4. Grignard additions to the formyl group of compound 7 in the presence of Lewis acids afforded diastereomerically pure secondary carbinols 8. Protection of the hydroxyl group and unmasking of