A novel protein modification generating an aldehyde group in sulfatases: its role in catalysis and disease

Structural variation in a novel zinc fin

Structural variation in a novel zinc finger protein and investigation of its role in Hirschsprung disease

✍ Scott D. Andrew; Michael J. Kuiper; Michael A. Wride; Fiona C. Mansergh; Derrick 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 277 KB

## Abstract Zinc finger transcription factors play essential roles in neural crest cell development. Even subtle disruptions of the function of these genes could contribute significantly to complex developmental phenotypes such as the multigenic disorder Hirschsprung disease (HSCR), a congenital fa