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A novel process related impurity and forced degradation study of synthetic wogonin: Development of a liquid chromatographic method for purity control

✍ Scribed by Ying Xia; Chunyong Wu; Wenyuan Liu; Feng Feng; Zhiyu Li


Book ID
118264270
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
359 KB
Volume
71
Category
Article
ISSN
0731-7085

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## Abstract A novel stability‐indicating high‐performance liquid chromatographic (HPLC) method was developed and validated for assay and determination of impurities of emtricitabine in drug substance. Emtricitabine was found to be degraded under acidic, alkaline, and oxidative stress conditions and