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A novel polymorphism (471C→T) in alpha-1-antitrypsin in a patient with asthma

✍ Scribed by Visva Pillay; David J. Halsall; Christine Gaillard; David A. Lomas; Ravi Mahadeva


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
18 KB
Volume
17
Category
Article
ISSN
1059-7794

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Genetic diversity of the alpha-1-antitry
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The highly polymorphic human alpha-1-antitrypsin (AAT) gene, more recently named SERPINA1, codes for the most abundant circulating plasma serine protease inhibitor, protease inhibitor 1 (PI). Most studies determining AAT haplotype frequencies have been restricted first by the limited accuracy of the