𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel palladium-catalyzed synthesis of β-carbolines: application in total synthesis of naturally occurring alkaloids

✍ Scribed by Shubhada W Dantale; Björn C.G Söderberg

Book ID
104205475
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
216 KB
Volume
59
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

Two naturally occurring b-carbolines, 6-methoxy-2-methyl-1,2,3,4-tetrahydro-b-carboline and bauerine A, have been prepared using a Stille-type coupling, followed by a palladium-phosphine catalyzed N-heteroannulation as the key steps.

📜 SIMILAR VOLUMES

The first total synthesis of the novel β
The first total synthesis of the novel β-carboline alkaloid oxopropaline G
✍ Tominari Choshi; Yuhji Matsuya; Maki Okita; Kazuya Inada; Eiichi Sugino; Satoshi 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 239 KB

The first total synthesis of the new type of cytocydal Pcarholine alkaloid oxopropaline G was achieved in 12 steps.

β-Carboline alkaloids 9 [1]. Total synth
β-Carboline alkaloids 9 [1]. Total synthesis of the β-carboline alkaloids arenarine A and (±)arenarine B
✍ Franz Bracher; Andreas Puzik 📂 Article 📅 2004 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 128 KB 👁 1 views

## Abstract The first total synthesis of the β‐carboline alkaloids arenarine A **(1)** and arenarine B **(2)** is described. Methanolysis of the α‐bromoketone **9** gives **1** in good yield. Alternatively **1** can be obtained from the diazoketone **11** with boron trifluoride/methanol in poor yie