This study reports the development of a novel osteochondral graft for cartilage repair. A technique of proteoglycan extraction via timed enzymatic digestion with hyaluronidase and trypsin and subsequent processing with a chloroform-methanol solution to remove cellular debris from a fresh-frozen bovi
✦ LIBER ✦
A novel osteochondral scaffold of ceramic–gelatin assembly for articular cartilage repair
✍ Scribed by Sio-Mei Lien; Chien-Hsiang Chien; Ta-Jen Huang
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 527 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0928-4931
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## Abstract In this study, we successfully developed two types of volume‐reduced three‐dimensional scaffolds, including cushion‐ and cylinder‐shape scaffolds, fabricated from chitosan‐based hyaluronic acid hybrid polymer fibers. Using these scaffolds combined with a bioreactor system, we regenerate