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A novel one-step procedure for the conversion of thymidine into 2,3?-anhydrothymidine

✍ Scribed by Rao, T. Sudhakar; Reese, Colin B.


Book ID
120189992
Publisher
The Royal Society of Chemistry
Year
1989
Tongue
English
Weight
203 KB
Volume
0
Category
Article
ISSN
0022-4936

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Two tin@) complexes, Sn(SPhh-and Sn(C4H406)g2-. besides NaHSo3. are involved in a procedure developed for the rapid transfmation at pH 5-6 of R-CHZ-NO2 into R-CHOH-S03Na. from which the de&d aldehydes have been isdated in 80-91% overall yields. llms, a new ahemative to the Nef maction is now in hand