𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel one-pot palladium-mediated synthesis of N-[(2-hydroxyphenyl)methyl]-N-(4-phenoxy-3-pyridinyl) acetamide, the precursor to [11C]PBR28, a PET biomarker for the peripheral benzodiazepine receptor

✍ Scribed by Raphaël Hoareau; Peter J.H. Scott


Book ID
104097765
Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
220 KB
Volume
51
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Radiosynthesis of 2-[6-chloro-2-(4-iodop
✍ C. Thominiaux; F. Mattner; I. Greguric; H. Boutin; F. Chauveau; B. Kuhnast; M.-C 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 145 KB

## Abstract Recently, a new 2‐(iodophenyl)imidazo[1,2‐__a__]pyridineacetamide series has been developed as iodine‐123‐labelled radioligands for imaging the peripheral benzodiazepine receptors using single photon emission tomography. Within this series, 2‐[6‐chloro‐2‐(4‐iodophenyl)‐imidazo[1,2‐__a__

Radiosynthesis of 7-chloro-N,N-dimethyl-
✍ Cyrille Thominiaux; Annelaure Damont; Bertrand Kuhnast; Stéphane Demphel; Stépha 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 168 KB

## Abstract SSR180575 (7‐chloro‐__N__,__N,__5‐trimethyl‐4‐oxo‐3‐phenyl‐3,5‐dihydro‐4__H__‐pyridazino[4,5‐__b__]indole‐1‐acetamide) is the lead compound of an original pyridazinoindole series of potent and highly selective TSPO (peripheral benzodiazepine receptor) ligands. Isotopic labeling of SSR18