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A Novel One-Pot Method for the Preparation of Pyrazoles by 1,3-Dipolar Cycloadditions of Diazo Compounds Generated in Situ

✍ Scribed by Aggarwal, Varinder K.; de Vicente, Javier; Bonnert, Roger V.


Book ID
111890025
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
46 KB
Volume
68
Category
Article
ISSN
0022-3263

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An intramolecular one-pot synthesis of s
✍ Marija N. Sakač; Andrea R. GakoviΔ‡; JΓ‘nos J. CsanΓ‘di; Evgenija A. DjurendiΔ‡; Oli πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 French βš– 258 KB

A novel synthetic route is reported for the preparation of steroidal triazoles via intramolecular 1,3-dipolar cycloaddition of a steroidal 16,17-seco-17-diazo-16-nitrile system. The structures of the products are established by X-ray and NMR studies. The in vitro antiproliferative activity of the st