A Novel Nucleophilic Approach to 1-Alkyladenosines. A Two-Step Synthesis of [1-15N]Adenosine from Inosine.
โ Scribed by Montserrat Terrazas; Xavier Ariza; Jaume Farras; Jaume Vilarrasa
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 21 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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Pilot-Scale Synthesis of a Novel Non-Xanthine Adenosine A 1 Receptor Antagonist. 1,3-Dipolar Cycloaddition of Pyridine N-Imine to an Acetylene. -A new, concise and efficient large scale procedure for the preparation of title compound FK838 (VII) is developed. It is based on a detailed investigation