A Novel Mycolactone from a Clinical Isolate of Mycobacterium ulcerans Provides Evidence for Additional Toxin Heterogeneity as a Result of Specific Changes in the Modular Polyketide Synthase

Cover Picture: A Novel Mycolactone from

Cover Picture: A Novel Mycolactone from a Clinical Isolate of Mycobacterium ulcerans Provides Evidence for Additional Toxin Heterogeneity as a Result of Specific Changes in the Modular Polyketide Synthase (ChemBioChem 4/2005)

✍ Hui Hong; Jonathan B. Spencer; Jessica L. Porter; Peter F. Leadlay; Tim Stinear 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 42 KB

**The cover picture shows** the structure (in red, right) of the lipophilic polyketide toxin mycolactone obtained from the reference Ghana strain of __Mycobacterium ulcerans__, the causative agent of the emerging disease Buruli ulcer, and that (in red, left) of a molecular variant of mycolactone new