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A Novel Mutation Which Enhances the Fluorescence of Green Fluorescent Protein at High Temperatures

✍ Scribed by Yukio Kimata; Masaharu Iwaki; Chun Ren Lim; Kenji Kohno


Book ID
115579911
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
651 KB
Volume
232
Category
Article
ISSN
0006-291X

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Hypermutation targets a green fluorescen
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Hypermutation introduces point mutations into the gene segments encoding immunoglobulin variable regions at a rate that is a million-fold higher than the spontaneous mutation rate in most of the genome. Because Ig enhancers are required to target hypermutation, transcription appears to play a critic