Shedding of mutant tumor necrosis factor
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Mary L. Huggins; Paul M. Radford; Richard S. McIntosh; Susan E. Bainbridge; Pete
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Article
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2004
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John Wiley and Sons
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English
⚖ 170 KB
👁 1 views
## Abstract ## Objective To investigate the effect of mutations in tumor necrosis factor receptor superfamily 1A (TNFRSF1A) on the ability of the receptors to be cleaved from the cell surface upon stimulation. The mutations we studied are associated with clinically distinct forms of TNF receptor–a