๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A novel mutation in GDF5 causes autosomal dominant symphalangism in two Chinese families

โœ Scribed by Xu Wang; Fuying Xiao; Qinbo Yang; Bo Liang; Zhaohui Tang; Linbin Jiang; Qihui Zhu; Wei Chang; Jiuxi Jiang; Chuanming Jiang; Xiang Ren; Jing-Yu Liu; Qing K. Wang; Mugen Liu


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
273 KB
Volume
140A
Category
Article
ISSN
1552-4825

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## Communicated by Christine Van Broeckhoven Hereditary spastic paraplegia (HSP) is a neurodegenerative disease characterized by lower-limb spasticity, hyperreflexia, progressive spastic gait abnormalities, and an extensor-plantar response. It is genetically very heterogeneous, with 28 Human Genome