A novel multicomponent reaction of dimethoxycarbene and DMAD with aldehydes and quinones: facile synthesis of dihydrofuran derivatives

✍ Scribed by Vijay Nair; S Bindu; Lakshmi Balagopal

• Publisher: Elsevier Science
• Year: 2001
• Tongue: French
• Weight: 62 KB
• Volume: 42
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)00070-3

✦ Synopsis

The zwitterionic species generated by the addition of dimethoxy carbene to dimethyl acetylenedicarboxylate (DMAD) is trapped by aldehydes and quinones to yield dihydrofuran derivatives in good yields.