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A novel microplate-based HPLC-fluorescence assay for determination of NADPH-cytochrome P450 reductase activity

✍ Scribed by Tomas Erban; Palmiro Poltronieri; Jitka Stara


Book ID
112013422
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
292 KB
Volume
26
Category
Article
ISSN
0269-3879

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## Abstract Cytochrome P450 enzymes are a family of heme‐containing proteins located throughout the body with roles in metabolism of endogenous and exogenous compounds. Among exogenous compounds, clinically relevant pharmaceutical agents are nearly all metabolized by P450 enzymes. However, the acti