A novel method to prepare size-regulated spheroids composed of human dermal fibroblasts

Regulation of fibrogenic/fibrolytic gene

Regulation of fibrogenic/fibrolytic genes by platelet-derived growth factor C, a novel growth factor, in human dermal fibroblasts

✍ Masatoshi Jinnin; Hironobu Ihn; Yoshihiro Mimura; Yoshihide Asano; Kenichi Yaman 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 257 KB 👁 1 views

## Abstract Platelet‐derived growth factor (PDGF) is a potent mitogenic and chemotactic cytokine, and PDGF‐C is a novel growth factor belonging to the PDGF family. In this study, to determine whether this growth factor can contribute to fibrosis and tissue remodeling, we examined the effect of PDGF