𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel method to identify high order gene-gene interactions in genome-wide association studies: Gene-based MDR

✍ Scribed by Oh, Sohee; Lee, Jaehoon; Kwon, Min-Seok; Weir, Bruce; Ha, Kyooseob; Park, Taesung


Book ID
114999603
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
959 KB
Volume
13
Category
Article
ISSN
1471-2105

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Increasing the power of identifying gene
✍ Charles Kooperberg; Michael LeBlanc 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB 👁 2 views

## Abstract In this paper we investigate the power to identify gene × gene interactions in genome‐wide association studies. In our analysis we focus on two‐stage analyses: analyses in which we only test for interactions between single nucleotide polymorphisms that show some marginal effect. We give

A novel method to identify gene–gene eff
✍ E.R. Martin; M.D. Ritchie; L. Hahn; S. Kang; J.H. Moore 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 354 KB

## Abstract It is now well recognized that gene–gene and gene–environment interactions are important in complex diseases, and statistical methods to detect interactions are becoming widespread. Traditional parametric approaches are limited in their ability to detect high‐order interactions and hand

Sample size requirements to detect gene-
✍ Cassandra E. Murcray; Juan Pablo Lewinger; David V. Conti; Duncan C. Thomas; W. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 209 KB 👁 2 views

Many complex diseases are likely to be a result of the interplay of genes and environmental exposures. The standard analysis in a genome-wide association study (GWAS) scans for main effects and ignores the potentially useful information in the available exposure data. Two recently proposed methods t