A novel method for the synthesis of 1(2H)-phthalazinones using silica-supported perchloric acid

✍ Scribed by Majid M. Heravi; Bita Baghernejad; Hossein A. Oskooie

• Publisher: Journal of Heterocyclic Chemistry
• Year: 2009
• Tongue: English
• Weight: 75 KB
• Volume: 46
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.77

✦ Synopsis

Abstract

magnified image

A simple and efficient synthesis of 1(2__H__)‐phthalazinone derivatives was achieved via reaction of phthalaldehydic acid and various phenyl hydrazines in acetonitrile using HClO~4~‐SiO~2~ as a catalyst in very good yields. J. Heterocyclic Chem., 46, 351 (2009).