Leptin induces phagocytosis of apoptotic
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Joy X. Jiang; Kenichiro Mikami; Vijay H. Shah; Natalie J. Torok
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Article
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2008
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John Wiley and Sons
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English
β 326 KB
Leptin, a profibrogenic cytokine, plays an important role in the development of non-alcoholic steatohepatitis. Leptin also regulates immune responses, including macrophage phagocytic activity. Stellate cells are key elements in liver fibrogenesis, and previously we have demonstrated that phagocytosi