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A novel mammalian cell-culture technique for consistent production of a well-tolerated and immunogenic trivalent subunit influenza vaccine

✍ Scribed by Arvydas Ambrozaitis; Nicola Groth; Roberto Bugarini; Vittoria Sparacio; Audino Podda; Maria Lattanzi


Book ID
116961871
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
428 KB
Volume
27
Category
Article
ISSN
0264-410X

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✍ Bernd Kalbfuss; Yvonne Genzel; Michael Wolff; Anke Zimmermann; Robert Morenweise 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 241 KB 👁 2 views

## Abstract A process scheme for the harvesting and concentration of cell culture‐derived human influenza A virus is presented. The scheme comprises two static filtration steps, chemical inactivation by β‐propiolactone and cross‐flow ultrafiltration. Human influenza A virus A/PR/8/34 (H1N1) was pro