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A novel macrolactamization of ω-(p-aminophenyl)carboxylic acid with 2,2′-dipyridyldisulfide-triphenylphosphine

✍ Scribed by Donglu Bai; Yiqun Shi

Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
162 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis

In terms of solvophobicity, acetonftrfk is selected OS a solvent to get accem to macroiactamization of cu-(p-aminophenyl) carboxylic acids (la-e) by using 2,2'-dipyridyIdimdjIdetriphenylphpht

a8 an activating reagent. The yields of am-macrolactams (2% b, c, e) are 58-70%.

📜 SIMILAR VOLUMES

2-(2-Aminophenyl)-acetaldehyde Dimethyl
2-(2-Aminophenyl)-acetaldehyde Dimethyl Acetal: A Novel Reagent for the Protection of Carboxylic Acids.
✍ Eri Arai; Hidetoshi Tokuyama; Martin S Linsell; Tohru Fukuyama 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 439 KB

The synthesis and use of 2-(2-aminophenyl)-acetaldehydedimethyl acetal 1 are described, The amides 2, derived from this amine and carboxylicacids, are stable under basic conditions and thus can be regardedas the protectedcarboxylicacids. The correspondingcarboxylicacids are regeneratedby conversion