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A novel insight into the mechanism of the antithrombotic action of defibrotide

✍ Scribed by Rosella Tettamanti; Giorgio Bianchi; Pierre Alain Vitte; Gabor Kato; Roberto Porta; Christoph Thiemermann; Rodolfo Pescador; Marisa Mantovani

Book ID
118345746
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
552 KB
Volume
51
Category
Article
ISSN
0024-3205

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## Abstract The biologically active metabolite of vitamin D, 1,25‐dihydroxyvitamin D~3~ (1,25(OH)~2~D~3~) is a secosteroid whose genomic mechanism of action is similar to that of other steroid hormones and is mediated by stereospecific interaction of 1,25(OH)~2~D~3~ with the vitamin D receptor (VDR