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A novel inhibitor of respiratory syncytial virus isolated from ethnobotanicals

✍ Scribed by Joshua O. Ojwang; Yan-Hong Wang; Philip R. Wyde; Nikolaus H. Fischer; Wolfgang Schuehly; James R. Appleman; Soreeta Hinds; Craig D. Shimasaki

Book ID: 113457245
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 333 KB
Volume: 68
Category: Article
ISSN: 0166-3542
DOI: 10.1016/j.antiviral.2005.09.003

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## Abstract The syntheses of tritiated and radio‐iodinated respiratory syncytial virus inhibitor photoaffinity labels are reported. ^3^H‐1‐Isopropyl‐3‐(1‐[2‐(3‐methyl‐3H‐diazirin‐3‐yl)‐ethyl]‐1H‐benzoimidazol‐2‐yl)methyl)‐1,3‐dihydrobenzoimid‐azol‐2‐one (**1**), was prepared in two steps by the ini