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A novel inhibitor of inducible nitric oxide synthase, ONO-1714, reduces dextran sodium sulfate-induced colitis in mice

✍ Scribed by Naito, Yuji; Yoshikawa, Toshikazu; Takagi, Tomohisa; Handa, Osamu; Ishikawa, Takeshi; Matsumoto, Naohisa; Matsuyama, Kiichi; Yagi, Nobuaki; Yoshida, Norimasa; Kondo, Motoharu

Book ID: 122786560
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 179 KB
Volume: 118
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(00)81310-4

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## Abstract The overproduction of reactive oxygen and nitrogen species (RONS) may play an important role in ulcerative colitis (UC)‐associated carcinogenesis. In order to study the role of nitric oxide (NO) in UC‐associated colorectal carcinogenesis, the development of colorectal carcinoma was stud