A novel infant acute lymphoblastic leukemia cell line with MLL-AF5q31 fusion transcript
β Scribed by Imamura, T; Morimoto, A; Ikushima, S; Kakazu, N; Hada, S; Tabata, Y; Yagi, T; Inaba, T; Hibi, S; Sugimoto, T
- Book ID
- 110055222
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 265 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0887-6924
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## Abstract __MLL__ gene rearrangements leading to production of MLL fusion proteins are commonly detected in infant leukemia patients; the most common __MLL__ fusion associated with infant leukemia is the __MLLβAF4__ fusion. A single case of chromosomal rearrangement leading to production of an __
## Abstract More than 30 fusions involving the __MLL__ gene at 11q23 have been reported in acute myeloid leukemia (AML). Some of these chimeras are rather common, such as __MLL/MLLT3__(__AF9__), but many are quite rare, with some, for example, __MLL/GRAF__, described only in a single case. The __ML
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