A novel industrial process for l-aspartic acid production using an ultrafiltration-membrane

✍ Scribed by H. Yamagata; M. Terasawa; H. Yukawa

• Book ID: 103934028
• Publisher: Elsevier Science
• Year: 1994
• Tongue: English
• Weight: 517 KB
• Volume: 22
• Category: Article
• ISSN: 0920-5861
• DOI: 10.1016/0920-5861(94)80127-4

✦ Synopsis

A novel industrial process for the production of L-aspartic acid was developed. This process is characterized by the use of intact cells of a coryneform bacterium, Brevibacteriumflavum which does not undergo autolysis, and by the use of an ultrafiltration-membrane for the separation and recycling of the cells. Unwanted formation of by-product, txralic acid, was selectively eliminated by heat treating cells prior to reaction. Improvement of the process is in progress based on genetic enginee~ng techniques.