A novel indole synthesis
โ Scribed by Howard Alper; John E. Prickett
- Book ID
- 104224809
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 100 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
IN attempts towards the synthesis of steroidal alkaloids1 we treated 5androstene-3B-ol-17-one with g-nitrobenzaldehyde in basic solution and obtained instead of the expected 16-(2-nitrobenzal) compound a yellow acidic product, m.p. 267-269' (dec.), in 75 per cent yield, to which structure Ia is attr
We wish to report a facile thermal rearrangement of an N-aryl propynylamine oxide to an indole. The present study, to our knowledge, is the first report of such a rearrangement. Compound 1 (89.5%; m.p. 76-77)\* was prepared by the condensation of l-(4-chlorophenoxy)-4chloro-2-butyne3 with two moles