Novel strategy for efficient screening a
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C. Perry Chou; Chih-Chang Yu; Wen-Jer Lin; Bau-Yuan Kuo; Wen-Chang Wang
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Article
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1999
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John Wiley and Sons
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English
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A novel and simple method of using penicillin for screening of mutant strains with a high penicillin acylase (PAC) activity was developed. Random mutagenesis was conducted using a PAC-producing strain resistant to 6-aminopenicillanic acid (6-APA) as the parent strain and mutants were screened with p