The most common causative diagnosis of hereditary small-vessel-disease of the brain, CADASIL, is due to highly stereotyped mutations in the NOTCH3 receptor. NOTCH3 has 33 exons but all CADASIL mutations occur within the Epidermal Growth Factor-like Repeats encoded by exons 2-24, lead to an odd numbe
A novel hereditary small vessel disease of the brain
β Scribed by Steve Verreault; Anne Joutel; Florence Riant; Georgina Neves; Mario Rui Silva; Jacqueline Maciazek; Elizabeth Tournier-Lasserve; Marie-Germaine Bousser; Hugues Chabriat
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 213 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0364-5134
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