A novel functionally deficient MYH variant in individuals with colorectal adenomatous polyposis

Clinical and screening implications of t

Clinical and screening implications of the I1307K adenomatous polyposis coli gene variant in Israeli Ashkenazi Jews with familial colorectal neoplasia : Evidence for a founder effect

✍ Paul Rozen; Tova Naiman; Hana Strul; Philipp Taussky; Nataly Karminsky; Ruth Sho 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB 👁 1 views

## Abstract ## BACKGROUND The authors previously found the I1307K adenomatous polyposis coli (__APC__) gene variant in 5% of Ashkenazi control participants, in 15.4% of those who had familial colorectal neoplasia, but also in 1.6% of non‐Ashkenazi control participants. In this study, they evaluate