𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells

✍ Scribed by Katsuhiko Muraki; Yuji Imaizumi

Book ID
111119525
Publisher
Cambridge University Press
Year
2001
Tongue
English
Weight
503 KB
Volume
537
Category
Article
ISSN
0022-3751

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Permeation properties of a non-selective
Permeation properties of a non-selective cation channel in human vascular endothelial cells
✍ B. Nilius πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 409 KB

Endothelial cells obtained from human umbilical chord have been studied by the patch clamp method. An ion channel is described that is activated by microM concentrations of histamine and shows a slow run-down in cell-attached patches. After excision, channel activity quickly runs down to zero open p

Characterisation of a sphingosine 1-phos
Characterisation of a sphingosine 1-phosphate-activated Ca2+ signalling pathway in human neuroblastoma cells
✍ Israel Ramos Villullas; Alison J. Smith; Robert P. Heavens; Peter B. Simpson πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 679 KB

## Abstract Sphingosine 1‐phosphate (S1P) has assumed great importance within neuroscience research because of putative links between S1P‐sensitive Edg receptors and neuroregeneration, cell survival, and alterations in neurite outgrowth. In the present study, we examined the mechanisms by which the

Endothelial cell migration in human plas
Endothelial cell migration in human plasma is enhanced by a narrow range of added sphingosine 1-phosphate: Implications for biomaterials design
✍ Shannon K. Alford; Megan M. Kaneda; Bradley K. Wacker; Donald L. Elbert πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 472 KB

## Abstract Sphingosine 1‐phosphate (S1P) promotes endothelial cell migration __in vitro__ and may potentially impact the endothelialization of implanted biomaterials. However, the effects of S1P on endothelial cells (EC) in flowing blood could be negligible due to preactivation of signaling cascad