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A novel frequency method for quantitative analysis of fluorescence dye concentration by using series photodetector frequency circuit system

✍ Scribed by Yuh Ming Hsu; Chung Cheng Chang


Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
737 KB
Volume
154
Category
Article
ISSN
0924-4247

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✦ Synopsis


This study reported the frequency characteristics of series photodetector frequency circuit system for detection of fluorescence dye concentration. In the condition of the same fluorescence intensity, the series photodetector frequency circuit system with higher responsivity of photodetector had higher frequency shift. The 100 MHz series photodetector frequency circuit system was applied to determine the fluorescence dye concentration of HEX by frequency shift. The correlation curve showed that the frequency shift was linearly related to the logarithm of fluorescence dye concentration from 100 pmol 3 l -1 to 10 amol 3 l -1 . The proposed method can be applied simply and the detection limit of fluorescence dye concentration was lower than the conventional fluorescence technique by 2-3 orders.